Medicinal chemistry

High school (ages 12+)
Science & Technology

Name:

Date:

Step 1 · Read the article

Open the article and read it at the level above. Then answer the questions below in your own words.

https://smallwhale.org/articles/medicinal-chemistry

Write what each word means, using the article.

Do not copy the article. Write two things you learned, the way you would explain them to a friend.

Answers below are taken from the article’s stored facts, so they match what the student read.

1. Who discovered Medicinal chemistry?Employs strategies like HTS, SAR analysis, and rational design
2. What is the core discipline?Integrates organic synthesis, physical chemistry, biochemistry, and pharmacology
3. What is the key historical figure?Paul Ehrlich pioneered the concept of selective toxicity with Salvarsan

Structure-Activity Relationship (SAR): The correlation between a molecule's chemical structure and its biological activity.
Pharmacokinetics: The study of how the body absorbs, distributes, metabolizes, and excretes drugs.
Lead Optimization: The process of modifying a promising drug candidate to improve its therapeutic properties.