Macrophage

High school (ages 12+)
Human Body

Name:

Date:

Step 1 · Read the article

Open the article and read it at the level above. Then answer the questions below in your own words.

https://smallwhale.org/articles/macrophage

Write what each word means, using the article.

Do not copy the article. Write two things you learned, the way you would explain them to a friend.

Answers below are taken from the article’s stored facts, so they match what the student read.

1. Who discovered Macrophage?1884
2. What is the discoverer?Élie Metchnikoff
3. What is the primary function?Phagocytosis of pathogens, cellular debris, and foreign substances
4. How do macrophages help fight infections?They recognize and swallow germs, break them down, and then show pieces of the germs to other immune cells to start a stronger defense.
5. Where can macrophages be found in the body?Macrophages live everywhere, such as in the liver (Kupffer cells), brain (microglia), lungs (alveolar macrophages), and bone (osteoclasts).

Phagocytosis: The cellular process of engulfing and internalizing particles or other cells.
Antigen Presentation: Displaying fragments of pathogens on cell surfaces to activate other immune cells.
Cytokines: Signaling proteins that mediate and regulate immunity, inflammation, and hematopoiesis.
MHC Class II: Surface molecules on antigen-presenting cells that display foreign antigens to T helper cells.