Coeliac disease

High school (ages 12+)
Human Body

Name:

Date:

Step 1 · Read the article

Open the article and read it at the level above. Then answer the questions below in your own words.

https://smallwhale.org/articles/coeliac-disease

Write what each word means, using the article.

Do not copy the article. Write two things you learned, the way you would explain them to a friend.

Answers below are taken from the article’s stored facts, so they match what the student read.

1. Where is Coeliac disease?Worldwide distribution, with varying prevalence rates
2. How big is Coeliac disease?Primarily the small intestine, but with systemic effects
3. How long is Coeliac disease?Increased risk of certain cancers and bone disease if untreated
4. What is the population affected?Estimated 1% of the global population, with a significant undiagnosed rate
5. What is the genetic predisposition?Strong association with HLA-DQ2 and HLA-DQ8 genes
6. What is coeliac disease and why does it happen?Coeliac disease is a condition where the body reacts badly to gluten, a protein found in wheat, barley, and rye. The reaction damages tiny finger‑like parts of the small intestine called villi, which makes it hard to absorb nutrients.

Autoimmune Response: An immune system reaction where the body mistakenly attacks its own healthy cells and tissues.
Villous Atrophy: The flattening and damage of the villi in the small intestine, hindering nutrient absorption.
Serological Tests: Blood tests that detect specific antibodies produced by the immune system in response to gluten.