Charcot–Marie–Tooth disease

High school (ages 12+)
Human Body

Name:

Date:

Step 1 · Read the article

Open the article and read it at the level above. Then answer the questions below in your own words.

https://smallwhale.org/articles/charcot-marie-tooth-disease

Write what each word means, using the article.

Do not copy the article. Write two things you learned, the way you would explain them to a friend.

Answers below are taken from the article’s stored facts, so they match what the student read.

1. Who discovered Charcot–Marie–Tooth disease?1886
2. What is the discoverers?Doctors Jean-Martin Charcot, Pierre Marie, and Howard Henry Tooth
3. What is the prevalence?Approximately 1 in 2,500 people worldwide
4. Why do people with CMT have trouble walking?Because the nerves in their feet and legs are damaged, so the signals that help muscles move are slowed or missing.
5. What makes CMT different from other nerve problems?CMT is caused by many different gene changes that affect the nerve’s protective covering or the nerve fibers themselves, so each person’s symptoms can be different.

Peripheral Neuropathy: Damage or dysfunction of nerves outside the brain and spinal cord, leading to sensory and motor deficits.
Axonopathy: A type of neuropathy where the primary damage occurs to the nerve cell's axon.
Myelinopathy: A type of neuropathy where the primary damage occurs to the myelin sheath surrounding nerve axons.